BENEFITS OF PET IN ISOTOPIC EXPLORATION

 

The thyroid gland
Isotopic exploration of the thyroid gland has an important place in the diagnosis of thyroid gland infections. The tracer injection will show the global size of the gland, the global level of fixation, the homogenity of the captation and the nature of the existence of the thyroidian nodules or not. The echography and the isotopic examinations are complimentary to one another and while each give unique physically different information. The scintigraphy allows for a select refined set of data that will predict whether further exploration (nodule cyctopunction) should be undertaken and/or surgical procedures should be undertaken, knowing that the latter can be diagnosised through echography alone (1/4 of the population).

SKELETAL SCINOTOGRAPHY
The principal examination in it’s field and is one of the major tools used by many centres in their exploration.

The examination is very precise and has evolved through advances in techinal advances in detection.

BENIGN PATHOLOGY
The skeletal scintigraphy has an important role to play in the diagnosis for symptoms thanks to its sensitivity but also in its ability to access the area under examination. In certain cases, once morphological analysis has been completed no further examinations are required. The examination is a osteomyelitic diagnosis of the necrosis or the osteochondrite, fracture fatigue, post traumatic fractures, osteo-cartilege tumors, benign Pagets syndrome, operable ectopic calcifications, algodystrophies, or a loosening of a prothesis.

MALIGNE PATHOLOGY
Due to the extensive range of the skeletal scintigraphy and its ability to detect anomolies, this examination is imperative for detection secondary sites. It is an essential part of the pre theraputic process and observation of osteopathic neoplasia of which prostratic cancer, breat cancer and broncho-pulmonary cancers can be detected.

It is also a useful tool in the early diagnosis of bone tumors or in secondary bone lesions without a known primary.

 

NUCLEAR CARDIOLOGY
This is still in its infancy but is developing quickly.

The Myocarde
Whether it is the use of Thallium or tracers introduced by perfusion this examination has an established place in the diagnosis of coronary illness. The diagnostic results it shows the presence of one or more ischemia areas. In the final prognosis it allows for the evaluation of the likelihood of heart attack and evaluates the results after revascularisation.

It has its place in the diagnosis of coronary illness in patients at risk during physical effort and in following patients undergoing treatment and the subsequent risk of intermediary lesions in coronography.

CAVITY EXPLORATION
This has a double role to play. In cardiology it measures the value of the left ventricle ejection and evaluates the partiel mobility ; in oncology it allows for early detection of cardiotoxique effects from certain chemotherapy treatments.

PULMONARY SCINTIGRAPHY
 

OTHER EXPLORATIONS
Although useful for other types of diagnosis it is not used frequently in the other types of explorations undertaken by the centre.

Uro-nephrology
Non invasive imaging and calculation of parenchymatic kidney function seperate from the arterial kidney perfusion (testing with enzyme inhibitors for conversion) the kidney excretion cavity (with diuretic testing) and kinetic utero-vesicules.

Neurology
Studies of the cerebral blood production, central nervous system receptors, circulation of cephalo-rachien liquids, the consumption of cerebral glucose in PET, investigations into epileptic symptoms.

Gastroenterology - hepatology
Hepatology scintigraphy, gastro-oesophagus transit studies, diagnosis of Meckel diverticulitis, localisation of digestive hemoraging.

Endocrinology
Scintigraphy of parathyrodian glands and suprarenal glands, saliva glands. Analogue scintigraphy for analysis of somatostatines in the diagnosis of neuro-endocrine tumors.

Infectious diseases
Diagnosis of deep seated infection by scintigraphy using gallium or marked leuocytes or by immuo-scintigraphy.

Lymphoscintigraphy
Diagnosis of sentiel ganglions in oncology particularly in breast cancer, pre-operative detection.

This list is not exhaustive and as technology advances the scope of investigations widens with the introduction of new tracers and products.